Active Pharmaceutical Ingredients
Active Pharmaceutical Ingredients (APIs) are the biologically active components used in the manufacturing of pharmaceutical drugs. These ingredients are responsible for the desired therapeutic effects of the medicine. While APIs form the essential part of any medication, they are often combined with other substances known as excipients, which help deliver the drug to the body and enhance its stability, flavor, or other properties.
The quality, purity, and potency of APIs are crucial as they directly impact the safety and efficacy of the drug. APIs are manufactured through various methods, including chemical synthesis, fermentation, or biological processes like biotechnology. The production of APIs is strictly regulated to ensure compliance with Good Manufacturing Practices (GMP) and quality standards set by health authorities such as the FDA or EMA.
APIs can be categorized based on their therapeutic applications, such as antibiotics, analgesics, anti-inflammatory agents, or anticancer drugs. With advancements in technology, many pharmaceutical companies focus on developing high-potency APIs (HPAPIs), which require precise handling due to their higher therapeutic activity, even in small doses.
| Therapeutic Category | API |
|---|---|
| Analgesics | Tapentadol Hcl |
| Anti Arthiritis | Ademetionine Disulfate Tosylate |
| Apremilast | |
| Tofacitinib Aspartate | |
| Antibacterial | Amoxicillin |
| Biapenem | |
| Ceftizoxime Sodium | |
| Delafloxacin mudlumine | |
| Fusidine | |
| Lincomycin Hydrochloride | |
| Neomycin Sulfate | |
| Nifuroazide | |
| Nitrofurantoin | |
| Polymyxin B Sulfate | |
| Posaconazole | |
| Tigecycline | |
| Voriconazole | |
| Zinc bacitracin | |
| Anti cancer | Aprepitant |
| Thymopentin | |
| Anticoagulant | Apixaban |
| Dabigatran Etexilate Mesylate | |
| Enoxaparin Sodium | |
| Heparin Sodium | |
| Nadroparin Calcium | |
| Rivaroxaban | |
| Anti Diabetic | Dapagliflozin |
| Imeglimin Hydrochloride | |
| Linagliptin | |
| Saxagliptin Hydrate | |
| Saxagliptin Hydrochloride | |
| Sitagliptin Phosphate | |
| Teneligliptin | |
| Teneligliptin Hydrobromide | |
| Tirzepatide | |
| Vildagliptin | |
| Antiemetic | Granisetron Hydrochloride |
| Anti-Fungal | Anidulafungin |
| Caspofungin acetate | |
| Clindamycin Phosphate | |
| Fluconazole | |
| Isavuconazole | |
| Ketoconazole | |
| Micafungin Sodium | |
| Posaconazole | |
| Voriconazole | |
| Antihistamine | Amlodipine Besylate |
| Desloratadine | |
| Antihypertensive | (S)-Amlodipine Nicotinate |
| (S)-Amlodipine/ Levamlodipine Besylate | |
| Felodipine | |
| Loratadine | |
| Losartan Potassium | |
| Minoxidil | |
| Nadolol | |
| Selexipag | |
| Anti-Platelet | Atorvastatin Calcium |
| Clopidogrel Besylate | |
| Clopidogrel Hydrogen Sulfate /Clopidogrel Bisulfate Form II | |
| Ticagrelor | |
| Antiretroviral | Atazanavir Sulfate |
| Bictegravir Sodium | |
| Cabotegravir Sodium / Cabotegravir | |
| Daclatasvir Dihydrochloride | |
| Darunavir/ Darunavir Ethanolate | |
| Dolutegravir Sodium | |
| Efavirenz | |
| Emtricitabine | |
| Etravirine | |
| Fosamprenavir Calcium | |
| Gadoteric Acid Meglumine | |
| Lamivudine | |
| Lopinavir | |
| Lopinavir + Ritonavir Premix | |
| Nevirapine | |
| Raltegravir Potassium | |
| Rilpivirine Hcl | |
| Ritonavir | |
| Saquinavir Mesylate | |
| Tenofovir Alafenamide Fumarate | |
| Tenofovir Alafenamide Monofumarate | |
| Tenofovir Disoproxil Fumarate | |
| Zidovudine | |
| Anti-TB | Bedaquiline Fumarate |
| Clofazimine | |
| Linezolid | |
| Rifapentine | |
| Terizidone | |
| Antiviral | Abacavir Sulfate |
| Acyclovir | |
| Entecavir(Monohydrate) | |
| Favipiravir | |
| Ledipasvir copovidone | |
| Molnupiravir | |
| Nirmatrelvir | |
| Oseltamivir Phosphate | |
| Sofosbuvir | |
| Valacyclovir HCI | |
| Valganciclovir Hcl | |
| Velpatasvir Copovidone | |
| Velpatasvir:PVP(1:1) | |
| Cardiovascular | Fosaprepitant Dimeglumine |
| CNS | Cannabidiol |
| Carbamazepine | |
| Eslicarbazepine Acetate | |
| Levetiracetam | |
| Oxcarbazepine | |
| Trazodone Hcl | |
| Contrast Agent | Gadobutrol |
| Gadopentetic Acid | |
| Iopromide | |
| Tirofiban | |
| Other APIs | Astaxanthin |
| Everolimus |